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Uncle DNA Testing

The uncle DNA test is an indirect way of establishing the identity of biological parents. The test will establish whether a male is the uncle of a potential niece or nephew. You should only use this test when the parents of the potential niece or nephew are not available for testing.

The uncle DNA test can establish the following:

  • How can I prove he is my nephew? Or is she my niece?
  • Is he my brother’s son? Or is she my brother’s daughter?
  • Is he my dad’s brother? Or is he my mum’s brother?
Uncle DNA Testing

How does the Uncle DNA Test work?

First, we create a DNA profile for each test participant. Next, the DNA profiles of the test participants are then compared. As a result, related individuals should have more DNA in common than unrelated individuals. Therefore, the DNA of related individuals will match at more locations than unrelated people.

This statistical analysis takes into consideration many different factors. These include the number of matches between the DNA profiles of each person. Also, how popular DNA markers are within a given population and ethnic group.

We use the values from the calculations to generate a percentage probability. In turn, this will show which relationship is most likely to exist between the individuals.

Frequently Asked Questions

How long does it take to get your uncle DNA test results back?

The analysis time needed in the lab for the uncle DNA test is three to five working days*. We will always endeavour to get the results to you as quickly as possible. However, during busy periods in the lab, results may only be available on the fifth working day.

* Quoted lead-times are based on from when samples are booked onto the laboratory system. Also, quoted lead-times do not apply when issues arise from documents or samples provided that do not meet our quality guidelines.

How do I order an uncle DNA test?

Here are the options available to you:

  • Call 0800 988 7107 to make an appointment at a DNA Clinic or order a *DNA self-collection Home Kit.
  • Call 0800 988 7107 to arrange a home visit from a sample collection officer.
  • You or your solicitor can contact us to organise a legal uncle DNA Test for court purposes.

* Please note, you can only use self-collection kits for peace of mind purposes only. This test cannot be used for legal purposes.

How do I collect my own uncle DNA samples?

We have provided some useful guidance for test participants collecting their own samples for a DNA uncle test.

How accurate is the uncle DNA test?

The uncle DNA test can provide accurate results. However, this is not a direct relationship test such as maternity or paternity testing. As a result, there is small a chance that the test could yield an inconclusive result. In the case of this test, the risk of an inconclusive result depends on who is available to take part in the test. Please call and speak to a Clinical Advisor for the latest information regarding inconclusivity rates.

If one known parent of the child is available for testing, then we will include them in the test for free. In this case, this could increase the accuracy of the test.

Please refer to the disclaimer on this page for further information.

How much does an uncle DNA test cost?

You can see examples of uncle DNA test prices using the link below.


Due to the science of complex DNA relationship testing and the chance nature associated with DNA inheritance, there is a small risk of an inconclusive result with this test. An inconclusive result means that the DNA analysed and compared between individuals does not provide enough evidence to establish the biological relationship being tested. The risk of obtaining an inconclusive result varies due to several factors including, the test participants available for testing, the individual’s specific DNA profiles and how unique or common they are and the number of locations on the gene tested.

It is important that you are aware of the risk of an inconclusive result before ordering or booking this test, as you will be signing consent to confirm your understanding and acceptance of this. Refunds will not be issued for inconclusive results.

However, we will always attempt to achieve a conclusive result for your DNA test. As such, there may be further options available to you to achieve this (additional fees apply). These are:

  1. The addition of other test participants. Crystal Health Group will recommend which individuals could be included to improve the chance of obtaining a conclusive result.
  2. Further analysis to compare additional loci (DNA locations).

If you are using the DNA Clinics service and booking an appointment, the above options will be explained to you. If you are ordering a self-collection kit, please call 0800 988 7107 and speak to a member of our team about these options before you order a DNA kit.

Local DNA Clinics, and mobile locations throughout the UK

For your convenience, we have a network of DNA Clinics throughout the UK. As a result, we can provide uncle test appointments for you in your local area. Alternatively, we can arrange for a certified sample collection officer to visit your home or other convenient location of your choice.